Tawau offers nonstop service to 8 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Sandakan | SDK | Malaysia | 175 km | 0h 40m | MY |
| Kota Kinabalu | BKI | Malaysia | 290 km | 0h 50m | AK, OD |
| Johor Bharu | JHB | Malaysia | 1,633 km | 2h 25m | AK |
| Kuala Lumpur | KUL | Malaysia | 1,830 km | 2h 55m | AK, MH, OD, FY |
| Macau | MFM | Macau SAR | 2,034 km | 3h 25m | FY |
| Hong Kong | HKG | Hong Kong SAR | 2,042 km | 3h 20m | HB |
| Guangzhou | CAN | China | 2,173 km | 3h 45m | AK |
| Shanghai | PVG | China | 2,994 km | 4h 55m | HO |