Saipan offers nonstop service to 14 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Tinian | TIQ | Northern Mariana Islands | 17 km | 0h 15m | S2 |
| Rota | ROP | Northern Mariana Islands | 117 km | 0h 30m | S2 |
| Guam | GUM | Guam | 205 km | 0h 45m | UA |
| Tokyo | NRT | Japan | 2,349 km | 3h 43m | UA |
| Manila | MNL | Philippines | 2,659 km | 4h 15m | PR |
| Seoul | ICN | Republic of Korea | 3,122 km | 4h 45m | 7C |
| Hong Kong | HKG | Hong Kong SAR | 3,439 km | 5h 15m | HX |