Southend offers nonstop service to 25 destinations, served by 1 airline.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Amsterdam | AMS | Netherlands | 291 km | 1h 5m | U2 |
| Paris | CDG | France | 315 km | 1h 10m | U2 |
| Jersey | JER | Jersey | 334 km | 1h 10m | U2 |
| Geneva | GVA | Switzerland | 713 km | 1h 30m | U2 |
| Grenoble | GNB | France | 770 km | 1h 30m | U2 |
| Munich | MUC | Germany | 871 km | 1h 40m | U2 |
| Berlin | BER | Germany | 883 km | 1h 40m | U2 |
| Salzburg | SZG | Austria | 980 km | 1h 45m | U2 |
| Pisa | PSA | Italy | 1,137 km | 2h 0m | U2 |
| Barcelona | BCN | Spain | 1,146 km | 2h 0m | U2 |
| Palma de Mallorca | PMI | Spain | 1,345 km | 2h 15m | U2 |
| Ibiza | IBZ | Spain | 1,411 km | 2h 20m | U2 |
| Alicante | ALC | Spain | 1,479 km | 2h 25m | U2 |
| Almeria | LEI | Spain | 1,654 km | 2h 45m | U2 |
| Malaga | AGP | Spain | 1,705 km | 2h 58m | U2 |
| Faro | FAO | Portugal | 1,755 km | 2h 55m | U2 |
| Enfidha | NBE | Tunisia | 1,887 km | 2h 55m | U2 |
| Malta | MLA | Malta | 2,063 km | 3h 5m | U2 |
| Rovaniemi | RVN | Finland | 2,174 km | 3h 15m | U2 |
| Marrakech | RAK | Morocco | 2,330 km | 3h 35m | U2 |
| Dalaman | DLM | Turkiye | 2,759 km | 3h 55m | U2 |
| Lanzarote | ACE | Spain | 2,779 km | 4h 5m | U2 |
| Antalya | AYT | Turkiye | 2,873 km | 4h 5m | U2 |
| Las Palmas | LPA | Spain | 2,949 km | 4h 20m | U2 |
| Tenerife | TFS | Spain | 2,984 km | 4h 20m | U2 |