Enfidha - Hammamet International Airport offers nonstop service to 42 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Verona | VRN | Italy | 1,035 km | 1h 50m | NO |
| Milan | MXP | Italy | 1,069 km | 1h 50m | NO |
| Geneva | GVA | Switzerland | 1,183 km | 2h 5m | U2 |
| Basel, Switzerland/Mulhouse | BSL | France | 1,301 km | 2h 18m | U2 |
| Luxembourg | LUX | Luxembourg | 1,543 km | 2h 30m | LG |
| Brussels | BRU | Belgium | 1,713 km | 3h 5m | TB |
| London | LGW | United Kingdom | 1,876 km | 3h 10m | U2 |
| Southend | SEN | United Kingdom | 1,887 km | 3h 5m | U2 |
| London | STN | United Kingdom | 1,932 km | 3h 10m | LS |
| London | LTN | United Kingdom | 1,953 km | 3h 15m | U2 |
| Bristol | BRS | United Kingdom | 1,996 km | 3h 15m | U2 |
| Birmingham | BHX | United Kingdom | 2,055 km | 3h 20m | LS, U2 |
| Leicestershire | EMA | United Kingdom | 2,076 km | 3h 5m | LS |
| Manchester | MAN | United Kingdom | 2,160 km | 3h 25m | LS, U2 |
| Liverpool | LPL | United Kingdom | 2,179 km | 3h 25m | U2 |
| Leeds | LBA | United Kingdom | 2,187 km | 3h 30m | LS |
| Newcastle | NCL | United Kingdom | 2,302 km | 3h 40m | U2 |
| Belfast | BFS | United Kingdom | 2,428 km | 3h 45m | U2 |
| Edinburgh | EDI | United Kingdom | 2,442 km | 3h 50m | U2 |
| Glasgow | GLA | United Kingdom | 2,470 km | 3h 40m | U2 |
| Madinah | MED | Saudi Arabia | 3,075 km | 4h 10m | SV |
| Jeddah | JED | Saudi Arabia | 3,206 km | 4h 40m | SV |