Pescara offers nonstop service to 25 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Bari | BRI | Italy | 258 km | 1h 0m | NO |
| Tirana | TIA | Albania | 471 km | 1h 15m | W4, FR |
| Milan | BGY | Italy | 507 km | 1h 15m | FR |
| Trapani | TPS | Italy | 523 km | 1h 15m | FR |
| Alghero | AHO | Italy | 530 km | 1h 15m | FR |
| Catania | CTA | Italy | 556 km | 1h 20m | FR, NO |
| Cagliari | CAG | Italy | 558 km | 1h 15m | FR |
| Milan | MXP | Italy | 563 km | 1h 20m | FR |
| Turin | TRN | Italy | 608 km | 1h 20m | FR |
| Memmingen | FMM | Germany | 690 km | 1h 25m | FR |
| Malta | MLA | Malta | 731 km | 1h 30m | FR |
| Prague | PRG | Czech Republic | 852 km | 1h 40m | FR |
| Girona | GRO | Spain | 944 km | 1h 50m | FR |
| Krakow | KRK | Poland | 952 km | 1h 50m | FR |
| Wroclaw | WRO | Poland | 985 km | 1h 55m | FR |
| Bucharest | OTP | Romania | 989 km | 1h 50m | FR, W4 |
| Hahn | HHN | Germany | 990 km | 1h 50m | FR |
| Luxembourg | LUX | Luxembourg | 1,009 km | 2h 15m | LG |
| Brussels | CRL | Belgium | 1,161 km | 2h 5m | FR |
| Dusseldorf | NRN | Germany | 1,186 km | 2h 5m | FR |
| Valencia | VLC | Spain | 1,274 km | 2h 15m | FR |
| Hamburg | HAM | Germany | 1,282 km | 2h 30m | NO |
| London | STN | United Kingdom | 1,484 km | 2h 35m | FR |
| Kaunas | KUN | Lithuania | 1,568 km | 2h 30m | FR |
| Sharm el Sheikh | SSH | Egypt | 2,428 km | 3h 30m | NO |