Duong Dong Airport offers nonstop service to 50 destinations, served by 24 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Phnom Penh | KTI | Cambodia | 166 km | 1h 5m | K6 |
| Can Tho | VCA | Viet Nam | 194 km | 1h 0m | VN |
| Ho Chi Minh City | SGN | Viet Nam | 300 km | 1h 5m | 9G, VJ, VN, VU |
| Siem Reap | SAI | Cambodia | 354 km | 1h 0m | KT |
| Bangkok | BKK | Thailand | 525 km | 1h 20m | 9G, VZ |
| Bangkok | DMK | Thailand | 554 km | 1h 20m | FD |
| Nha Trang | CXR | Viet Nam | 605 km | 1h 20m | 9G, C6 |
| Da Nang | DAD | Viet Nam | 794 km | 1h 45m | 9G, C6, VJ |
| Kuala Lumpur | KUL | Malaysia | 858 km | 1h 45m | 9G, AK |
| Singapore | SIN | Singapore | 974 km | 1h 55m | 9G, TR, VJ |
| Haiphong | HPH | Viet Nam | 1,214 km | 2h 5m | 9G, VJ |
| Hanoi | HAN | Viet Nam | 1,237 km | 2h 5m | 9G, VJ, VN |
| Kunming | KMG | China | 1,656 km | 3h 20m | DR |
| Hong Kong | HKG | Hong Kong SAR | 1,712 km | 3h 5m | 9G, UO, VJ |
| Chengdu | TFU | China | 2,230 km | 3h 25m | 9G, TV |
| Shalu | RMQ | Taiwan | 2,351 km | 3h 40m | JX |
| Taipei | TPE | Taiwan | 2,458 km | 3h 40m | 9G, JX, VJ |
| Xian | XIY | China | 2,731 km | 3h 55m | MU |
| Shanghai | PVG | China | 2,963 km | 4h 55m | MU |
| Busan | PUS | Republic of Korea | 3,751 km | 5h 25m | LJ, VJ, ZE |
| Seoul | ICN | Republic of Korea | 3,768 km | 5h 30m | 7C, 9G, KE, LJ, TW, VJ, ZE |
| Almaty | ALA | Kazakhstan | 4,507 km | 7h 50m | KC |
| Tashkent | TAS | Uzbekistan | 4,838 km | 7h 25m | C6, HY |
| Astana | NQZ | Kazakhstan | 5,414 km | 8h 50m | KC |
| Moscow | SVO | Russia | 7,625 km | 10h 50m | SU |