Port Hedland International offers nonstop service to 6 destinations, served by 3 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Karratha | KTA | Australia | 197 km | 0h 40m | GD |
| Newman | ZNE | Australia | 357 km | 1h 20m | GD |
| Broome | BME | Australia | 464 km | 1h 5m | GD |
| Perth | PER | Australia | 1,307 km | 2h 10m | QF, VA |
| Christmas Island | XCH | Christmas Island | 1,767 km | 2h 35m | QF |
| Cocos Islands | CCK | Cocos (Keeling) Islands | 2,496 km | 3h 30m | QF |