Leipzig Halle offers nonstop service to 36 destinations, served by 14 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Frankfurt | FRA | Germany | 299 km | 1h 0m | LH |
| Vienna | VIE | Austria | 482 km | 1h 15m | OS |
| Brussels | BRU | Belgium | 544 km | 1h 20m | 2L |
| Kerkyra | CFU | Greece | 1,442 km | 2h 20m | DI |
| Palma de Mallorca | PMI | Spain | 1,510 km | 2h 30m | DI, EW |
| Istanbul | IST | Turkiye | 1,693 km | 2h 58m | TK |
| Bodrum | BJV | Turkiye | 1,991 km | 3h 20m | VF |
| Chania | CHQ | Greece | 2,004 km | 3h 0m | DI |
| Kos | KGS | Greece | 2,005 km | 3h 0m | DI |
| Heraklion | HER | Greece | 2,065 km | 3h 5m | DI, XR |
| Rhodes | RHO | Greece | 2,090 km | 3h 5m | DI |
| Dalaman | DLM | Turkiye | 2,094 km | 3h 10m | XQ |
| Antalya | AYT | Turkiye | 2,181 km | 3h 15m | PC, XC, XQ |
| Tbilisi | TBS | Georgia | 2,705 km | 3h 45m | A9 |
| Funchal | FNC | Portugal | 3,139 km | 4h 45m | DI |
| Hurghada | HRG | Egypt | 3,244 km | 4h 35m | NE |
| Puerto del Rosario | FUE | Spain | 3,351 km | 4h 55m | DI |
| Las Palmas | LPA | Spain | 3,481 km | 5h 10m | DI, KK |
| Tenerife | TFS | Spain | 3,537 km | 5h 5m | DI |