Ishigaki offers nonstop service to 26 destinations, served by 8 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Miyakojima | MMY | Japan | 114 km | 0h 30m | NH, NU |
| Yonaguni | OGN | Japan | 128 km | 0h 30m | NU |
| Taipei | TPE | Taiwan | 314 km | 1h 10m | IT |
| Okinawa | OKA | Japan | 397 km | 1h 0m | 6J, NH, NU |
| Kaohsiung | KHH | Taiwan | 446 km | 1h 10m | IT |
| Hong Kong | HKG | Hong Kong SAR | 1,078 km | 2h 15m | UO |
| Fukuoka | FUK | Japan | 1,183 km | 2h 5m | MM |
| Seoul | ICN | Republic of Korea | 1,463 km | 2h 40m | LJ |
| Osaka | KIX | Japan | 1,540 km | 2h 15m | MM, NH, NU |
| Osaka | ITM | Japan | 1,580 km | 2h 18m | NH |
| Nagoya | NGO | Japan | 1,678 km | 2h 20m | NH |
| Tokyo | HND | Japan | 1,939 km | 2h 43m | JL, NH |
| Tokyo | NRT | Japan | 1,998 km | 2h 50m | MM |