El Calafate offers nonstop service to 7 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Ushuaia | USH | Argentina | 566 km | 1h 20m | AR, FO |
| Trelew | REL | Argentina | 936 km | 1h 40m | AR |
| San Carlos de Bariloche | BRC | Argentina | 1,018 km | 1h 45m | AR |
| Santiago | SCL | Chile | 1,878 km | 2h 55m | H2 |
| Buenos Aires | EZE | Argentina | 2,038 km | 3h 0m | AR, FO, JA |
| Buenos Aires | AEP | Argentina | 2,069 km | 3h 0m | AR, FO, JA |
| Cordoba | COR | Argentina | 2,204 km | 3h 15m | AR, FO |