Fergana Airport offers nonstop service to 22 destinations, served by 8 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Tashkent | TAS | Uzbekistan | 230 km | 0h 50m | C6, HY, UH |
| Novosibirsk | OVB | Russia | 1,819 km | 2h 45m | HY, S7 |
| Surgut | SGC | Russia | 2,337 km | 3h 30m | UT |
| Kazan | KZN | Russia | 2,363 km | 3h 45m | HY |
| Irkutsk | IKT | Russia | 2,807 km | 4h 10m | S7 |
| Zhukovsky | ZIA | Russia | 2,979 km | 4h 28m | U6 |
| Moscow | DME | Russia | 2,988 km | 4h 40m | HH, U6 |
| Moscow | VKO | Russia | 3,032 km | 4h 43m | DP, HY, UT |
| Saint Petersburg | LED | Russia | 3,579 km | 5h 10m | HH, HY |
| Istanbul | IST | Turkiye | 3,591 km | 5h 50m | C6 |
| Jeddah | JED | Saudi Arabia | 3,703 km | 7h 0m | C6 |