Daytona Beach Intl offers nonstop service to 11 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Atlanta | ATL | USA | 589 km | 1h 29m | DL |
| Charlotte | CLT | USA | 669 km | 1h 46m | AA |
| Raleigh/Durham | RDU | USA | 771 km | 1h 43m | MX |
| Wilmington | ILG | USA | 1,266 km | 2h 13m | XP |
| Akron | CAK | USA | 1,301 km | 2h 21m | MX |
| New York | JFK | USA | 1,432 km | 2h 30m | B6 |
| Westchester County | HPN | USA | 1,477 km | 2h 40m | MX |
| New Haven | HVN | USA | 1,531 km | 2h 34m | XP |
| Hartford | BDL | USA | 1,603 km | 2h 38m | MX |
| Providence | PVD | USA | 1,640 km | 2h 43m | MX |
| Boston | BOS | USA | 1,718 km | 2h 52m | B6 |