Daytona Beach Intl offers nonstop service to 21 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Atlanta | ATL | USA | 589 km | 1h 30m | DL |
| Charlotte | CLT | USA | 669 km | 1h 44m | AA |
| Raleigh/Durham | RDU | USA | 771 km | 1h 42m | MX |
| Wilmington | ILG | USA | 1,266 km | 2h 16m | XP |
| Akron | CAK | USA | 1,301 km | 2h 16m | MX |
| New York | LGA | USA | 1,442 km | 2h 50m | DL |
| Detroit | DTW | USA | 1,459 km | 2h 48m | DL |
| New Haven | HVN | USA | 1,531 km | 2h 36m | XP |
| Hartford | BDL | USA | 1,603 km | 2h 40m | MX |
| Providence | PVD | USA | 1,640 km | 2h 43m | MX |