Sapporo offers nonstop service to 94 destinations, served by 39 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Hakodate | HKD | Japan | 133 km | 0h 40m | NH |
| Kushiro | KUH | Japan | 207 km | 0h 45m | NH |
| Memanbetsu | MMB | Japan | 234 km | 0h 45m | JL, NH |
| Aomori | AOJ | Japan | 242 km | 0h 50m | JL, NH |
| Rishiri | RIS | Japan | 268 km | 0h 55m | NH |
| Nakashibetsu | SHB | Japan | 280 km | 0h 50m | NH |
| Wakkanai | WKJ | Japan | 290 km | 0h 55m | NH |
| Akita | AXT | Japan | 373 km | 1h 5m | NH |
| Hanamaki | HNA | Japan | 376 km | 0h 55m | JL |
| Yamagata | GAJ | Japan | 498 km | 1h 18m | JH |
| Sendai | SDJ | Japan | 520 km | 1h 10m | FW, HD, JL, MM, NH |
| Niigata | KIJ | Japan | 579 km | 1h 25m | JH, NH |
| Fukushima | FKS | Japan | 626 km | 1h 30m | NH |
| Omitami | IBR | Japan | 741 km | 1h 25m | BC |
| Toyama | TOY | Japan | 783 km | 1h 30m | NH |
| Tokyo | NRT | Japan | 786 km | 1h 50m | GK, IJ, MM, NH |
| Matsumoto | MMJ | Japan | 802 km | 1h 40m | JH |
| Tokyo | HND | Japan | 819 km | 1h 40m | BC, HD, JL, NH |
| Komatsu | KMQ | Japan | 840 km | 1h 35m | NH |
| Shizuoka | FSZ | Japan | 937 km | 1h 58m | JH, NH |
| Nagoya | NGO | Japan | 976 km | 1h 50m | BC, HD, IJ, JL, MM, NH |
| Osaka | ITM | Japan | 1,039 km | 2h 0m | JL, NH |
| Kobe | UKB | Japan | 1,063 km | 2h 0m | BC, HD, NH |
| Osaka | KIX | Japan | 1,082 km | 2h 23m | GK, JL, MM, NH |
| Izumo | IZO | Japan | 1,116 km | 1h 55m | JL |
| Okayama | OKJ | Japan | 1,119 km | 2h 0m | NH |
| Tokushima | TKS | Japan | 1,140 km | 2h 0m | JL |
| Hiroshima | HIJ | Japan | 1,199 km | 2h 5m | JL, NH |
| Daegu | TAE | Republic of Korea | 1,357 km | 3h 0m | TW |
| Busan | PUS | Republic of Korea | 1,386 km | 2h 50m | 7C, BX, LJ, TW, ZE |
| Cheongju | CJJ | Republic of Korea | 1,387 km | 2h 53m | |
| Fukuoka | FUK | Japan | 1,416 km | 2h 45m | BC, GK, HD, JH, JL, MM, NH |
| Seoul | ICN | Republic of Korea | 1,424 km | 3h 10m | 7C, KE, LJ, OZ, TW, WE, ZE |
| Shanghai | PVG | China | 2,182 km | 4h 20m | 9C, MU |
| Okinawa | OKA | Japan | 2,239 km | 4h 0m | MM |
| Taipei | TPE | Taiwan | 2,712 km | 4h 23m | BR, CI, FD, IT, JX, TR, VZ |
| Shalu | RMQ | Taiwan | 2,822 km | 4h 55m | JX |
| Kaohsiung | KHH | Taiwan | 2,987 km | 4h 45m | IT, SL |
| Hong Kong | HKG | Hong Kong SAR | 3,426 km | 5h 50m | CX, HB, HX |
| Manila | MNL | Philippines | 3,705 km | 6h 10m | 5J, PR |
| Bangkok | DMK | Thailand | 5,063 km | 7h 25m | XJ |
| Bangkok | BKK | Thailand | 5,070 km | 7h 0m | TG |
| Singapore | SIN | Singapore | 5,924 km | 8h 35m | SQ |
| Kuala Lumpur | KUL | Malaysia | 5,944 km | 8h 40m | D7 |
| Vancouver | YVR | Canada | 6,900 km | 8h 15m | AC |
| San Francisco | SFO | USA | 7,717 km | 9h 5m | UA |
| Sydney | SYD | Australia | 8,550 km | 10h 55m | QF |