Calicut offers nonstop service to 36 destinations, served by 12 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Bengaluru | BLR | India | 297 km | 1h 10m | 6E, IX |
| Chennai | MAA | India | 502 km | 1h 40m | 6E |
| Hyderabad | HYD | India | 725 km | 1h 25m | 6E |
| Mumbai | BOM | India | 939 km | 1h 55m | 6E, SG |
| Delhi | DEL | India | 1,931 km | 3h 5m | 6E |
| Muscat | MCT | Oman | 2,325 km | 3h 45m | IX, OV, WY |
| Salalah | SLL | Oman | 2,447 km | 3h 58m | IX, OV |
| Al Ain | AAN | United Arab Emirates | 2,594 km | 4h 0m | IX |
| Ras al-Khaimah | RKT | United Arab Emirates | 2,646 km | 3h 50m | IX |
| Sharjah | SHJ | United Arab Emirates | 2,663 km | 3h 50m | G9, IX |
| Dubai | DXB | United Arab Emirates | 2,673 km | 4h 15m | 6E, FZ, IX, SG |
| Abu Dhabi | AUH | United Arab Emirates | 2,688 km | 4h 0m | 3L, 6E, EY, IX |
| Doha | DOH | Qatar | 3,002 km | 4h 15m | IX, QR |
| Bahrain | BAH | Bahrain | 3,141 km | 4h 35m | IX |
| Dammam | DMM | Saudi Arabia | 3,225 km | 5h 0m | 6E, IX |
| Riyadh | RUH | Saudi Arabia | 3,441 km | 5h 10m | IX, SV, XY |
| Kuwait | KWI | Kuwait | 3,528 km | 5h 25m | IX |
| Jeddah | JED | Saudi Arabia | 4,087 km | 6h 25m | 6E, IX, SV |