La Calera Airport offers nonstop service to 8 destinations, served by 3 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Guadalajara | GDL | Mexico | 271 km | 1h 6m | Y4 |
| Mexico City | MEX | Mexico | 536 km | 1h 23m | AM |
| Dallas | DFW | USA | 1,239 km | 2h 13m | AA |
| Tijuana | TIJ | Mexico | 1,765 km | 2h 50m | Y4 |
| Los Angeles | LAX | USA | 1,963 km | 3h 10m | Y4 |
| San Jose | SJC | USA | 2,442 km | 3h 50m | Y4 |
| Oakland | OAK | USA | 2,485 km | 4h 6m | Y4 |
| Chicago | MDW | USA | 2,514 km | 3h 43m | Y4 |