Trenton Mercer offers nonstop service to 18 destinations, served by 3 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Charleston | CHS | USA | 943 km | 2h 6m | MX |
| Orlando | SFB | USA | 1,404 km | 2h 29m | G4 |
| Orlando | MCO | USA | 1,442 km | 2h 48m | F9 |
| Vero Beach | VRB | USA | 1,492 km | 2h 50m | MX |
| Tampa | TPA | USA | 1,537 km | 2h 52m | F9 |
| Saint Petersburg | PIE | USA | 1,550 km | 2h 46m | G4 |
| Punta Gorda | PGD | USA | 1,623 km | 2h 53m | G4 |
| Fort Lauderdale | FLL | USA | 1,651 km | 2h 59m | G4 |
| Fort Myers | RSW | USA | 1,654 km | 3h 5m | MX |