Tirupati offers nonstop service to 9 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Bengaluru | BLR | India | 204 km | 1h 5m | 6E |
| Vijayawada | VGA | India | 347 km | 1h 10m | 6E |
| Hyderabad | HYD | India | 415 km | 1h 25m | 6E, AI, 9I |
| Shivamogga | RQY | India | 425 km | 1h 5m | S5 |
| Rajahmundry | RJA | India | 455 km | 1h 45m | 9I |
| Vishakhapatnam | VTZ | India | 600 km | 2h 0m | 6E |
| Mumbai | NMI | India | 910 km | 1h 45m | 6E |
| Mumbai | BOM | India | 933 km | 1h 45m | 6E |
| Delhi | DEL | India | 1,671 km | 2h 45m | 6E |