Bolshoye Savino offers nonstop service to 49 destinations, served by 18 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Kazan | KZN | Russia | 484 km | 1h 10m | RT, Y7 |
| Samara | KUF | Russia | 613 km | 1h 25m | RT |
| Usinsk | USK | Russia | 903 km | 1h 55m | RT |
| Surgut | SGC | Russia | 1,048 km | 2h 55m | UT |
| Naryan-Mar | NNM | Russia | 1,090 km | 1h 48m | 7R |
| Kogalym | KGP | Russia | 1,130 km | 2h 5m | RT |
| Moscow | SVO | Russia | 1,149 km | 2h 15m | DP, SU |
| Moscow | VKO | Russia | 1,169 km | 2h 10m | DP |
| Saint Petersburg | LED | Russia | 1,490 km | 2h 25m | DP, SU |
| Novosibirsk | OVB | Russia | 1,662 km | 2h 30m | S7 |
| Mineralnye Vody | MRV | Russia | 1,766 km | 3h 35m | A4 |
| Makhachkala | MCX | Russia | 1,779 km | 2h 50m | A4 |
| Minsk | MSQ | Belarus | 1,792 km | 3h 5m | WZ |
| Adler/Sochi | AER | Russia | 1,959 km | 3h 55m | DP, EO, N4, SU |
| Noril'sk | NSK | Russia | 1,968 km | 3h 10m | Y7 |
| Baku | GYD | Azerbaijan | 1,987 km | 3h 0m | IO |
| Gorno-Altaysk | RGK | Russia | 2,002 km | 2h 50m | RT |
| Tashkent | TAS | Uzbekistan | 2,077 km | 3h 10m | C6 |
| Batumi | BUS | Georgia | 2,080 km | 3h 45m | WZ |
| Yerevan | EVN | Armenia | 2,143 km | 3h 30m | 5G |
| Namangan | NMA | Uzbekistan | 2,184 km | 3h 10m | HY |
| Kaliningrad | KGD | Russia | 2,187 km | 3h 50m | N4 |
| Antalya | AYT | Turkiye | 2,977 km | 5h 18m | 2S, DP, SU, U6, ZF |
| Sharm el Sheikh | SSH | Egypt | 3,728 km | 6h 28m | SU |
| Hurghada | HRG | Egypt | 3,830 km | 6h 35m | SU |