Isle of Man offers nonstop service to 13 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Belfast | BHD | United Kingdom | 99 km | 0h 35m | EI |
| Dublin | DUB | Ireland | 129 km | 0h 50m | EI |
| Liverpool | LPL | United Kingdom | 144 km | 0h 40m | U2, LM |
| Manchester | MAN | United Kingdom | 175 km | 0h 50m | LM, U2 |
| Edinburgh | EDI | United Kingdom | 222 km | 1h 0m | LM |
| Birmingham | BHX | United Kingdom | 265 km | 1h 0m | LM |
| Bristol | BRS | United Kingdom | 327 km | 1h 0m | U2 |
| London | LTN | United Kingdom | 376 km | 1h 0m | U2 |
| London | LHR | United Kingdom | 405 km | 1h 35m | LM |
| London | LCY | United Kingdom | 426 km | 1h 35m | LM |
| London | LGW | United Kingdom | 444 km | 1h 20m | U2 |
| Sonderborg | SGD | Denmark | 937 km | 2h 30m | 6I |
| Copenhagen | CPH | Denmark | 1,119 km | 2h 30m | 6I |