Handan Airport offers nonstop service to 26 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Hohhot | HET | China | 531 km | 1h 15m | G5 |
| Dalian | DLC | China | 682 km | 1h 20m | G5 |
| Hangzhou | HGH | China | 893 km | 2h 0m | GJ |
| Shanghai | PVG | China | 906 km | 1h 55m | MU |
| Chongqing | CKG | China | 1,046 km | 1h 55m | G5 |
| Xining | XNN | China | 1,108 km | 2h 15m | GJ |
| Chengdu | TFU | China | 1,155 km | 2h 0m | 3U |
| Chengdu | CTU | China | 1,173 km | 2h 10m | 3U |
| Harbin | HRB | China | 1,413 km | 2h 30m | LT |
| Shenzhen | SZX | China | 1,540 km | 2h 15m | G5, LT |
| Nanning | NNG | China | 1,656 km | 3h 0m | GX |
| Haikou | HAK | China | 1,878 km | 3h 25m | GX |
| Sanya | SYX | China | 2,078 km | 3h 30m | GX |