Jazan offers nonstop service to 20 destinations, served by 10 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Jeddah | JED | Saudi Arabia | 639 km | 1h 25m | F3, SV, XY |
| Madinah | MED | Saudi Arabia | 898 km | 2h 0m | F3 |
| Addis Ababa | ADD | Ethiopia | 967 km | 2h 40m | ET |
| Riyadh | RUH | Saudi Arabia | 989 km | 1h 50m | F3, SV, XY |
| Khartoum | KRT | Sudan | 1,082 km | 2h 30m | J4 |
| Dammam | DMM | Saudi Arabia | 1,295 km | 2h 10m | F3, XY |
| Tabuk | TUU | Saudi Arabia | 1,411 km | 2h 40m | F3 |
| Dubai | DXB | United Arab Emirates | 1,617 km | 2h 50m | FZ |
| Sharjah | SHJ | United Arab Emirates | 1,634 km | 2h 45m | G9 |
| Cairo | CAI | Egypt | 1,854 km | 3h 0m | E5, NP, SM |