Dubai Al Maktoum offers nonstop service to 29 destinations, served by 15 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Riyadh | RUH | Saudi Arabia | 854 km | 2h 0m | XY |
| Sary | SRY | Iran | 1,315 km | 2h 0m | |
| Jeddah | JED | Saudi Arabia | 1,675 km | 3h 5m | XY |
| Groznyy | GRV | Russia | 2,218 km | 3h 50m | UT |
| Tashkent | TAS | Uzbekistan | 2,236 km | 2h 50m | HH |
| Mineralnye Vody | MRV | Russia | 2,407 km | 3h 55m | A4 |
| Adler/Sochi | AER | Russia | 2,482 km | 3h 50m | A4, WZ, U6 |
| Krasnodar | KRR | Russia | 2,659 km | 4h 0m | SU |
| Male | MLE | Maldives | 3,018 km | 4h 30m | B4 |
| Bucharest | OTP | Romania | 3,411 km | 5h 30m | A2 |
| Yekaterinburg | SVX | Russia | 3,567 km | 5h 5m | U6, SU |
| Moscow | DME | Russia | 3,671 km | 5h 40m | U6, S7 |
| Tyumen | TJM | Russia | 3,677 km | 5h 10m | UT |
| Moscow | VKO | Russia | 3,708 km | 5h 50m | UT |
| Timisoara | TSR | Romania | 3,806 km | 6h 5m | A2 |
| Novosibirsk | OVB | Russia | 4,032 km | 5h 40m | S7 |
| Surgut | SGC | Russia | 4,279 km | 6h 0m | UT |
| Saint Petersburg | LED | Russia | 4,329 km | 6h 15m | SU |
| Prague | PRG | Czech Republic | 4,483 km | 7h 0m | QS |
| Munich | MUC | Germany | 4,582 km | 7h 10m | B4 |
| Berlin | BER | Germany | 4,634 km | 7h 0m | EW |
| Milan | MXP | Italy | 4,725 km | 7h 0m | B4 |
| Zurich | ZRH | Switzerland | 4,784 km | 7h 40m | B4 |
| Stockholm | ARN | Sweden | 4,812 km | 7h 35m | D8 |
| Copenhagen | CPH | Denmark | 4,844 km | 7h 20m | D8, SK |
| Hanover | HAJ | Germany | 4,877 km | 7h 25m | EW |
| Cologne | CGN | Germany | 4,989 km | 7h 30m | EW |
| Luxembourg | LUX | Luxembourg | 5,014 km | 8h 0m | LG |
| Oslo | OSL | Norway | 5,165 km | 7h 50m | D8 |