Sentani offers nonstop service to 13 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Wamena | WMX | Indonesia | 242 km | 0h 50m | IL, IW, SJ |
| Oksibil | OKL | Indonesia | 258 km | 0h 50m | IL |
| Yahukimo | DEX | Indonesia | 277 km | 0h 45m | IL |
| Tanahmerah | TMH | Indonesia | 390 km | 1h 5m | IL |
| Tembagapura | TIM | Indonesia | 457 km | 1h 10m | GA, SJ, JT |
| Serui | ZRI | Indonesia | 501 km | 1h 20m | IL |
| Biak | BIK | Indonesia | 513 km | 1h 10m | SJ, JT |
| Nabire | NBX | Indonesia | 571 km | 1h 40m | IW, SJ |
| Merauke | MKQ | Indonesia | 658 km | 1h 20m | GA, JT |
| Manokwari | MKW | Indonesia | 742 km | 1h 25m | JT |
| Sorong | SOQ | Indonesia | 1,042 km | 1h 50m | JT, SJ |
| Ujung Pandang | UPG | Indonesia | 2,344 km | 3h 20m | ID, JT, QG, SJ |
| Jakarta | CGK | Indonesia | 3,777 km | 5h 5m | GA, ID |