Aeroporto de Porto Seguro offers nonstop service to 15 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Salvador | SSA | Brazil | 398 km | 1h 20m | AD, G3 |
| Belo Horizonte | CNF | Brazil | 625 km | 1h 20m | AD, G3 |
| Rio De Janeiro | GIG | Brazil | 829 km | 1h 40m | G3, LA |
| Brasilia | BSB | Brazil | 947 km | 1h 50m | LA |
| Uberlandia | UDI | Brazil | 1,007 km | 1h 50m | AD |
| Ribeirao Preto | RAO | Brazil | 1,053 km | 1h 50m | AD |
| Goiania | GYN | Brazil | 1,083 km | 1h 55m | AD |
| Sao Paulo | GRU | Brazil | 1,094 km | 2h 5m | G3, LA |
| Campinas | VCP | Brazil | 1,114 km | 2h 5m | AD |
| Sao Paulo | CGH | Brazil | 1,122 km | 2h 10m | AD, G3, LA |
| Sao Jose Do Rio Preto | SJP | Brazil | 1,191 km | 2h 0m | AD |
| Baura-Arealva | JTC | Brazil | 1,225 km | 2h 5m | AD |
| Presidente Prudente | PPB | Brazil | 1,443 km | 2h 25m | AD |
| Buenos Aires | AEP | Argentina | 2,783 km | 4h 10m | AR, G3 |
| Buenos Aires | EZE | Argentina | 2,810 km | 4h 10m | G3 |