Bukhara offers nonstop service to 19 destinations, served by 8 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Urgench | UGC | Uzbekistan | 382 km | 0h 50m | HY |
| Tashkent | TAS | Uzbekistan | 439 km | 1h 20m | C6, HY, UH |
| Makhachkala | MCX | Russia | 1,446 km | 2h 45m | WZ |
| Yekaterinburg | SVX | Russia | 1,908 km | 3h 5m | WZ |
| Moscow | DME | Russia | 2,621 km | 4h 10m | HH |
| Moscow | VKO | Russia | 2,665 km | 4h 10m | HY, UT |
| Moscow | SVO | Russia | 2,678 km | 4h 20m | SU |
| Istanbul | IST | Turkiye | 3,011 km | 4h 45m | TK |
| Jeddah | JED | Saudi Arabia | 3,127 km | 6h 30m | C6 |
| Saint Petersburg | LED | Russia | 3,257 km | 5h 10m | HY |