Bukhara offers nonstop service to 10 destinations, served by 9 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Urgench | UGC | Uzbekistan | 382 km | 0h 50m | HY |
| Tashkent | TAS | Uzbekistan | 439 km | 1h 0m | HY, C6, UH |
| Makhachkala | MCX | Russia | 1,446 km | 2h 43m | WZ |
| Yekaterinburg | SVX | Russia | 1,908 km | 3h 10m | WZ |
| Novosibirsk | OVB | Russia | 2,168 km | 3h 20m | HY |
| Moscow | DME | Russia | 2,621 km | 4h 10m | HH |
| Moscow | VKO | Russia | 2,665 km | 4h 10m | UT, HY |
| Moscow | SVO | Russia | 2,678 km | 4h 5m | SU, DP |
| Istanbul | IST | Turkiye | 3,011 km | 4h 50m | TK |
| Saint Petersburg | LED | Russia | 3,257 km | 5h 10m | HY, HH |