Hamilton offers nonstop service to 36 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| New York | JFK | USA | 1,226 km | 2h 30m | AA, B6, DL |
| New York | LGA | USA | 1,241 km | 2h 30m | DL |
| Boston | BOS | USA | 1,242 km | 2h 30m | B6 |
| New York | EWR | USA | 1,253 km | 2h 32m | UA |
| Westchester County | HPN | USA | 1,255 km | 2h 20m | |
| Philadelphia | PHL | USA | 1,261 km | 2h 25m | AA |
| Baltimore | BWI | USA | 1,318 km | 2h 35m | |
| Providenciales | PLS | Turks and Caicos Islands | 1,391 km | 2h 35m | |
| Halifax | YHZ | Canada | 1,394 km | 2h 31m | |
| Charlotte | CLT | USA | 1,534 km | 3h 7m | AA |
| Orlando | SFB | USA | 1,634 km | 3h 0m | |
| Montreal | YUL | Canada | 1,649 km | 2h 45m | |
| Orlando | MCO | USA | 1,652 km | 3h 0m | |
| Fort Lauderdale | FLL | USA | 1,653 km | 3h 5m | |
| Miami | MIA | USA | 1,679 km | 3h 12m | AA |
| Toronto | YYZ | Canada | 1,809 km | 3h 15m | AC |
| Atlanta | ATL | USA | 1,847 km | 3h 15m | DL |
| London | LHR | United Kingdom | 5,533 km | 6h 45m | BA |