Asmara Intl offers nonstop service to 14 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Port Sudan | PZU | Sudan | 507 km | 1h 0m | 3T, J4 |
| Khartoum | KRT | Sudan | 683 km | 1h 0m | 3T |
| Jeddah | JED | Saudi Arabia | 706 km | 1h 30m | XY |
| Cairo | CAI | Egypt | 1,812 km | 2h 50m | MS |
| Abu Dhabi | AUH | United Arab Emirates | 1,931 km | 3h 40m | EY |
| Dubai | DXB | United Arab Emirates | 2,039 km | 3h 40m | FZ |
| Istanbul | IST | Turkiye | 3,040 km | 4h 35m | TK |